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Diabetes insipidus (DI) is a condition caused by hyposecretion of, or insensitivity to the effects of, antidiuretic hormone (ADH), also known as arginine vasopressin (AVP). ADH is synthesised in the hypothalamus and transported as neurosecretory vesicles to the posterior pituitary. There.

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Diabetes insipidus, also called DI, is a rare condition that leads to frequent urination (passing a lot of clear, urine) and excessive thirst. Learn more from the experts at hormone.org.

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Diabetes insipidus is a rare disorder that occurs when a person s kidneys pass an abnormally large volume of urine that is insipid—dilute and odorless. In most people, the kidneys pass about 1 to 2 quarts of urine a day. In people with diabetes insipidus, the kidneys can pass 3 to 20 quarts.
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Central diabetes insipidus (DI) is a form of DI that occurs when the body has lower than normal levels of antidiuretic hormone (vasopressin), which is characterized by frequent urination. Diabetes insipidus is subdivided into central and nephrogenic DI. Two other forms are gestational DI and primary polydipsia (dipsogenic.
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Diabetes insipidus in infants can be particularly difficult to diagnose. Because the two main symptoms of this disorder are an increased level of thirst and an excessive amount of urine, it can be difficult to distinguish normal developing behaviors or symptoms of this disorder.
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Nephrogenic diabetes insipidus is a disorder in which a defect in the small tubes (tubules) in the kidneys causes a person to produce a large amount of urine. Nephrogenic diabetes insipidus occurs when the kidney tubules, which allow water to be removed from the body or reabsorbed, do not respond to a chemical in the body called antidiuretic hormone or vasopressin.




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